Invokana Linked to Kidney Cancer

Invokana, a popular type 2 diabetes drug, has been linked to serious side effects, including kidney cancer.  If you took Invokana and developed renal cancer, or other kidney issues, it may be important to consider your potential legal claim. Our legal team is ready to help you navigate the next steps – to speak with our team about your circumstances and help you understand your legal options, please call us at 1.800.755.0098 or fill out a free case review form.


In 2013, the FDA approved Invokana, a sodium–glucose cotransporter 2 (SGLT2) inhibitor prescribed to people suffering from type 2 diabetes. Its main function is to inhibit normal kidney function to reduce the amount of glucose in the bloodstream. However, while studies show it can help manage diabetes, a new study found that people who use Invokana may be more likely to be diagnoses with kidney cancer.

In August 2017, The New England Journal of Medicine published the results of a study conducted by the CANVAS Program Collective Group that examined the effects of drugs like Invokana on kidney functions. The trials were composed of more than 10,000 participants with type 2 diabetes. During this study it was discovered that patients taking Invokana had a 300% increased chance to develop renal (kidney) cancer.

In addition to the heightened risk of renal cancer, other serious issues have reportedly been associated with Invokana, such as:

  • Kidney failure or impairment
  • Kidney stones
  • Ketoacidosis
  • Urinary tract infections (UTI)
  • Bladder Cancer
  • Fournier’s gangrene of the genitals


August 29, 2018: FDA Warns About Rare Occurrences of a Serious Infection of the Genital Area with SGLT2 Inhibitors for Diabetes,

August 17, 2017: Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes,

May 6, 2015: Unanswered Questions about Canagliflozin (INVOKANA), Institute for Safe Medication Practices


If you or a loved one has developed kidney cancer or other complications while taking Invokana, Zimmerman Reed’s experienced team welcomes your questions. Fill out a free case review or call us at 1.800.755.0098 and we will review your situation to determine if you have a claim, at no cost to you.